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the addition or withdrawal of phenytoin or carbamazepine to topamax therapy may require an adjustment in dosage of the latter.
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with lamictal lamotrigine , the level of topamax increased 15 , and with depakote valproic acid , both drugs concentrations were lowered 11-14 .
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brian loftus states that some patients lose as much as 15 to 20 percent of their body weight while taking between 100 and 200 mg topamax, and they report that the weight loss is effortless.
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